On the quest for undiscovered plant DNA receptors

Jordi Gamir, Isaac Vega Muñoz, Leila Rassizadeh, Martin Heil

Te invitamos a leer el artículo "On the quest for undiscovered plant DNA receptors" publicado en "Trends in Plant Science" en el que colaboró el Dr. Martin Heil de Cinvestav Irapuato.

Autores:

Jordi Gamir, Isaac Vega Muñoz, Leila Rassizadeh, Martin Heil

Resumen:

The presence of unexpected DNA in cellular compartments acts as a danger signal that activates immune responses. In mammals, delocalized self-DNA triggers strong inflammatory responses crucial for antiviral immunity and cancer control. In plants, application of exogenous self-DNA increases resistance to pathogens and herbivores. Although several mammalian DNA receptors have been identified with distinct subcellular localizations and mechanisms to discriminate between microbial and mitochondrial DNA, no DNA receptors have been identified in plants. Here, we show current evidence for different potential response mechanisms for DNA perception and consider several hypothetical mechanisms for its recognition in plants. Finally, we provide a potential framework for finding plant self-DNA receptors in the future.