An evolutionary continuum between non-coding and coding DNA

Josué Barrera Redondo & Susana M. Coelho

Te invitamos a leer el artículo "An evolutionary continuum between non-coding and coding DNA" publicado en "Evolutionary genetics" en el que colaboró el Dr. Josué Barrera Redondo de Cinvestav Irapuato.

Autores:

Mónica Roció Sánchez Tovar,  Ireri Alejandra Carbajal Valenzuela,  Pablo Luis Godínez Mendoza,  Rafael F. Rivera Bustamante,  Diana L. Saavedra Trejo,  Ramon Gerardo Guevara González,  Irineo Torres Pacheco

Resumen:
From the early 1970s, with the publication of Evolution by Gene Duplication by Susumu Ohno, up until the early 2000s, the prevailing view in molecular evolution was that new genes must at least partially evolve from pre-existing genes. As such, some research during this time focused on identifying the earliest existing ‘founder’ genes that were present in the last universal common ancestor. However, this long-standing view that protein-coding genes must evolve from ancestral genes was challenged by the discovery of ‘de novo genes’ (which arise from non-coding DNA) in a 2006 paper by Levine et al., as discussed in a previous Journal Club by Li Zhao. The paper by Levine et al. was crucial in providing evidence for an alternative mechanism to generate new genes, but this example was notably still viewed as more of an evolutionary curiosity than a common process.