Examen de Maestría

Marisol Navarro Miranda

Les invitamos al examen final de la Biol. Marisol Navarro Miranda para obtener el grado de Maestría en Biología Integrativa
Lunes 17 de febrero
15:00 Seminario público
16:00 Lectura del acta
Departamento de Ingeniería Genética, Aula E3, Unidad Irapuato

Biología Integrativa | Cinvestav Irapuato 
Examen para obtener el grado de Maestría que presenta:
Biol. Marisol Navarro Miranda

“Genomic bases of pairwise antagonistic interactions in bacterial isolates from Cuatro Ciénegas, Coahuila, Mexico”

Lunes 17 de febrero del 2025

  
SEMINARIO PUBLICO 15:00 hrs
LECTURA DEL ACTA Y AGRADECIMIENTOS 16:00 hrs
 

Departamento de Ingeniería Genética, Aula E3
Unidad Irapuato
  
DIRECTORAS DE TESIS 
Dra. Maribel Hernández Rosales
Dra. Gabriela Olmedo Álvarez
 
COMITÉ TUTORIAL 
Dra. Laila Pamela Partida Martínez
Dr. Luis José Delaye Arredondo 

RESUMEN 

Microbial communities are the unseen architects of ecosystems, yet the genomic blueprints guiding their assembly remain elusive. Although microbial composition is well studied, the role of lineage-specific genomic traits in shaping ecological interactions remains largely unexplored. In this work, we investigated 78 bacterial isolates mostly from the Bacillota phylum from oligotrophic sediments of the Cuatro Ciénegas Basin (CCC), Coahuila, Mexico, to reveal how intra- and interspecies genomic features govern community assembly under nutrient-limited conditions. By integrating a network approach to pairwise interactions, genomic profiling, and metabolic predictions, we uncover taxonomic group-specific patterns in metabolic modules and Biosynthetic Gene Clusters (BGCs), which likely play key roles in antagonistic and cooperative microbial interactions. Our findings show that highly competitive bacteria possess enhanced antibiotic potential, while others exhibit resistance traits that likely buffer the community, contributing to structural stability. Strikingly, lineage-specific BGCs, which suggest limited gene exchange likely driven by adaptation to the oligotrophic conditions of the CCB sediments, may also play a crucial role in facilitating niche differentiation and mediating competitive dynamics through metabolite production. This study provides a framework to decode complex microbial interactions, offering insights into genomic traits possibly contributing to ecological coexistence under nutrient-limited conditions. Moreover, it highlights the potential of lineage-specific secondary metabolism as a reservoir for novel compounds, with implications for microbial assemblages in both natural and applied contexts.